The invention pertains to the dystrophin-glycoprotein complex of mammalian skeletal muscle and a method of isolating said complex. The components of the complex and methods of separating and isolating said components also pertain to the invention. In addition, the invention further relates to a method of diagnosing muscular dystrophy by detecting and quantifying the loss of a non-dystrophin component of the dystrophin-glycoprotein complex with said loss being indicative of muscular dystrophy.
Patent
Measuring non-dystrophin proteins and diagnosing muscular dystrophy
United States Patent and Trademark Office
02/16/1993
Abstract
Details
- Title: Subtitle
- Measuring non-dystrophin proteins and diagnosing muscular dystrophy
- Creators
- Kevin P Campbell (Inventor)James M Ervasti (Inventor)Kay Ohlendieck (Inventor)Mitchell G Gaver (Inventor)Steven D Kahl (Inventor)
- Contributors
- University of Iowa Research Foundation (Iowa City, IA, US) (Assignee)
- Resource Type
- Patent
- Publisher
- United States Patent and Trademark Office; United States
- Patent
- US Patent 5,187,063; Published; 07/527,583; 05/23/1990; 435/7.21; 436/63, 436/518, 436/811
- Number of pages
- 19 pages
- Language
- English
- Date published
- 02/16/1993
- Academic Unit
- Iowa Neuroscience Institute; UI Research Foundation
- Record Identifier
- 9983761951502771
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