The present invention provides novel pseudotyped retroviral vectors that can transduce human and other cells. Vectors are provided that are packaged efficiently in packaging cells and cell lines to generate high titer recombinant virus stocks expressing novel envelope glycoproteins. The present invention further relates to compositions for gene therapy.
Patent
Methods for producing and using in vivo pseudotyped retroviruses using envelope glycoproteins from lymphocytic choriomeningitis virus (LCMV)
United States Patent and Trademark Office
11/14/2006
Abstract
Details
- Title: Subtitle
- Methods for producing and using in vivo pseudotyped retroviruses using envelope glycoproteins from lymphocytic choriomeningitis virus (LCMV)
- Creators
- Paul B McCray Jr (Inventor)Beverly L Davidson (Inventor)
- Contributors
- University of Iowa Research Foundation (Iowa City, IA, US) (Assignee)
- Resource Type
- Patent
- Publisher
- United States Patent and Trademark Office; United States
- Patent
- US Patent 7,135,339; United States Patent and Trademark Office (United States, Alexandria) - USPTO; Published; 10/718,262; 11/20/2003
- Number of pages
- 26 pages
- Language
- English
- Date published
- 11/14/2006
- Academic Unit
- UI Research Foundation; Microbiology and Immunology; Stead Family Department of Pediatrics; Internal Medicine; Pulmonary Medicine
- Record Identifier
- 9983761976702771
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