The present invention relates to methods of reducing a level of a target mRNA in a well-differentiated airway epithelial cell by contacting the cell with a sensitizing agent followed by contacting the cell with a therapeutic RNAi agent.
Patent
Methods to enhance RNAi oligonucleotide delivery to respiratory epithelial cells
United States Patent and Trademark Office
03/01/2016
Abstract
Details
- Title: Subtitle
- Methods to enhance RNAi oligonucleotide delivery to respiratory epithelial cells
- Creators
- Paul B McCray Jr (Inventor)Beverly L Davidson (Inventor)Sateesh Krishnamurthy (Inventor)
- Contributors
- University of Iowa Research Foundation (Iowa City, IA, US) (Assignee)
- Resource Type
- Patent
- Publisher
- United States Patent and Trademark Office; United States
- Patent
- US Patent 9,272,016; United States Patent and Trademark Office (United States, Alexandria) - USPTO; Published; 13/828,488; 03/14/2013
- Number of pages
- 30 pages
- Language
- English
- Date published
- 03/01/2016
- Academic Unit
- UI Research Foundation; Microbiology and Immunology; Stead Family Department of Pediatrics; Internal Medicine; Pulmonary Medicine
- Record Identifier
- 9983761980402771
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