The present invention provides in certain embodiments a method of treating autosomal dominant non-syndromic hearing loss (ADNSHL) in a patient in need thereof comprising: (a) identifying a mutation in an ADNSHL-causing gene, (b) preparing a ADNSHL therapeutic miRNA, and (c) administering to the patient a pharmaceutical composition comprising the ADNSHL therapeutic miRNA and a pharmaceutically acceptable carrier.
Patent
Methods to prevent and treat autosomal dominant non-syndromic hearing loss
United States Patent and Trademark Office
09/12/2017
Abstract
Details
- Title: Subtitle
- Methods to prevent and treat autosomal dominant non-syndromic hearing loss
- Creators
- Richard J H Smith (Inventor)Seiji Shibata (Inventor)
- Contributors
- University of Iowa Research Foundation (Iowa City, IA, US) (Assignee)
- Resource Type
- Patent
- Publisher
- United States Patent and Trademark Office; United States
- Patent
- US Patent 9,758,781; Published; 14/850,740; 09/10/2015
- Number of pages
- 34 pages
- Language
- English
- Date published
- 09/12/2017
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Molecular Physiology and Biophysics; Anatomy and Cell Biology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; UI Research Foundation; Otolaryngology; Internal Medicine
- Record Identifier
- 9983761993002771
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