The invention pertains to pure, native dystrophin of mammalian skeletal muscle and a method of purifying dystrophin from mammalian skeletal muscle. The invention further pertains to a method of diagnosing muscular dystrophy by detecting the loss or abnormal structure of pure, native dystrophin from mammalian skeletal muscle. The detection of a loss of dystrophin or an abnormal structure of dystrophin is indicative of muscular dystrophy.
Patent
Purified, native dystrophin
United States Patent and Trademark Office
07/04/1995
Abstract
Details
- Title: Subtitle
- Purified, native dystrophin
- Creators
- Kevin P Campbell (Inventor)Steven D Kahl (Inventor)James M Ervasti (Inventor)
- Contributors
- University of Iowa Research Foundation (Iowa City, IA, US) (Assignee)
- Resource Type
- Patent
- Publisher
- United States Patent and Trademark Office; United States
- Patent
- US Patent 5,430,129; Published; 07/642,202; 01/16/1991; 530/395; 530/397, 530/413, 530/414, 530/416, 530/417
- Number of pages
- 14 pages
- Language
- English
- Date published
- 07/04/1995
- Academic Unit
- Neurology; Molecular Physiology and Biophysics; Iowa Neuroscience Institute; UI Research Foundation
- Record Identifier
- 9983761995402771
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