The present invention is directed to RNA interference (RNAi) molecules targeted against a nucleic acid sequence, and methods of using these RNAi molecules to reduce off-target toxicity.
Patent
Reduction of off-target RNA interference toxicity
United States Patent and Trademark Office
09/04/2012
Abstract
Details
- Title: Subtitle
- Reduction of off-target RNA interference toxicity
- Creators
- Beverly L Davidson (Inventor)Alejandro Mas Monteys (Inventor)Jodi L Mcbride (Inventor)Ryan Boudreau (Inventor)
- Contributors
- University of Iowa Research Foundation (Iowa City, IA, US) (Assignee)
- Resource Type
- Patent
- Publisher
- United States Patent and Trademark Office; United States
- Patent
- US Patent 8,258,286; Published; 12/129,523; 05/29/2008; 536/24.5; 435/320.1, 536/23.1
- Number of pages
- 132 pages
- Language
- English
- Date published
- 09/04/2012
- Academic Unit
- Iowa Neuroscience Institute; UI Research Foundation; Internal Medicine
- Record Identifier
- 9983761956802771
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