The present invention is directed to RNA interference (RNAi) molecules targeted against a nucleic acid sequence, and methods of using these RNAi molecules to reduce off-target toxicity.
Patent
Reduction of off-target RNA interference toxicity
United States Patent and Trademark Office
09/03/2013
Abstract
Details
- Title: Subtitle
- Reduction of off-target RNA interference toxicity
- Creators
- Beverly L Davidson (Inventor)Alejandro Mas Monteys (Inventor)Jodi L Mcbride (Inventor)Ryan Boudreau (Inventor)
- Contributors
- University of Iowa Research Foundation (Iowa City, IA, US) (Assignee)
- Resource Type
- Patent
- Publisher
- United States Patent and Trademark Office; United States
- Patent
- US Patent 8,524,881; Published; 13/552,454; 07/18/2012; 536/24.5
- Number of pages
- 134 pages
- Language
- English
- Date published
- 09/03/2013
- Academic Unit
- Iowa Neuroscience Institute; UI Research Foundation; Internal Medicine
- Record Identifier
- 9983762100102771
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