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Stable congener of 2',3'-dideoxyadenosine
Patent   Open access

Stable congener of 2',3'-dideoxyadenosine

Vasu Nair and Greg S Buenger
United States Patent and Trademark Office
05/07/1991
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Stable congener of 23-dideoxyadenosine284.10 kBDownloadView
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Abstract

The preseent invention is concerned with congeners of 2',3'-dideoxyadenosine (ddA) with modifications at the 2- and 8- positions to increase stability of the compounds from the standpoint of resistance to deamination and hydrolytic cleavage of the glycosidic bond.

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