The present invention provides methods directed to detecting antibodies that specifically bind to a varicella zoster polypeptide, detecting the presence of a varicella zoster virus in an animal, diagnosing a disease caused by varicella zoster virus, and detecting a varicella zoster virus having a single nucleotide polymorphism in ORF68. The present invention also provides a vaccine composition, a method for producing a modified attenuated varicella zoster virus, isolated polynucleotides, and isolated polypeptides, and viruses.
Patent
Variant varicella-zoster viruses and methods of use
United States Patent and Trademark Office
01/18/2005
Abstract
Details
- Title: Subtitle
- Variant varicella-zoster viruses and methods of use
- Creators
- Charles F Grose (Inventor)Richard Santos (Inventor)
- Contributors
- University of Iowa Research Foundation (Iowa City, IA, US) (Assignee)
- Resource Type
- Patent
- Publisher
- United States Patent and Trademark Office; United States
- Patent
- US Patent 6,843,997; United States Patent and Trademark Office (United States, Alexandria) - USPTO; Published; 10/288,823; 11/06/2002
- Number of pages
- 99 pages
- Language
- English
- Date published
- 01/18/2005
- Academic Unit
- UI Research Foundation; Infectious Disease (Pediatrics)
- Record Identifier
- 9983761949702771
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