Preprint
A Systematic Review of Interventions for Persons Living With Dementia: The Geriatric ED Guidelines 2.0
medRxiv
Cold Spring Harbor Laboratory Press, 1.1
03/03/2025
DOI: 10.1101/2025.02.28.25323113
PMCID: PMC11908280
PMID: 40093231
Abstract
The increasing prevalence of dementia poses significant challenges for emergency department (ED) care, as persons living with dementia (PLWD) more frequently experience adverse outcomes such as delirium, prolonged stays, and higher mortality rates. Despite advancements in care strategies, a critical gap remains in understanding how ED interventions impact outcomes in this vulnerable population. This systematic review aims to identify evidence-based ED care interventions tailored to PLWD to improve outcomes.
A systematic review was conducted in Ovid MEDLINE, Cochrane Library (Wiley), Scopus (Elsevier), and ProQuest Dissertations & Theses Global through September 2024. The review protocol was registered on PROSPERO (CRD42024586555). Eligible studies included randomized controlled trials, observational studies, and quality improvement initiatives focused on ED interventions for PLWD. Data extraction and quality assessment were performed independently by two reviewers, with disagreements resolved through discussion. Outcomes included patient satisfaction, ED revisits, functional decline, and mortality.
From 3,305 screened studies, six met the inclusion criteria. Interventions included nonpharmacologic therapies (e.g., music and light therapy), specialized geriatric ED units, and assessment tools, such as for pain. Tailored interventions including geriatric emergency units and community paramedic care transitions were effective in reducing 30-day ED revisits and hospitalizations. However, heterogeneity in study designs and outcomes precluded meta-analysis. Risk of bias ranged from low to moderate.
This review underscores the urgent need for standardized and evidence-based interventions in ED settings for PLWD. Approaches including multidisciplinary care models and non-pharmacologic therapies demonstrated potential for improving outcomes. Future research should prioritize consistent outcome measures, interdisciplinary collaboration, and person-centered care strategies to enhance the quality and equity of ED services for PLWD.
Tailored interventions such as geriatric ED units and community paramedic care transitions significantly reduce ED revisits and hospital admissions among persons living with dementia.
Non-pharmacologic therapies, including music and light interventions, show potential for improving patient outcomes, though results are heterogeneous and require further validation.
The review highlights the urgent need for standardized protocols and interdisciplinary approaches to enhance emergency care for this vulnerable population.
This paper addresses critical knowledge gaps concerning emergency care for persons living with dementia, offering evidence-based insights to improve outcomes and guide the development of standardized, person-centered interventions in ED settings.
Details
- Title: Subtitle
- A Systematic Review of Interventions for Persons Living With Dementia: The Geriatric ED Guidelines 2.0
- Creators
- Sangil Lee - Department of Emergency Medicine, University of Iowa Carver College of MedicineMichelle Suh - University of ChicagoLuna Ragsdale - Duke University HospitalJustine Seidenfeld - Durham VA Health Care SystemJames D. van Oppen - University of SheffieldLauren Lapointe-Shaw - University of TorontoCarolina Diniz Hooper - Faculdade Ciências Médicas de Minas GeraisJames Jaramillo - Quinnipiac UniversityAnnie B. Wescott - Northwestern UniversityKaiho Hirata - International University of Health and WelfareMaura Kennedy - Harvard Medical SchoolLauren Cameron Comasco - Corewell Health William Beaumont University HospitalChristopher R. Carpenter - Mayo ClinicTeresita M Hogan - University of ChicagoShan W. Liu - Harvard Medical SchoolGeriatric ED Guidelines dementia writing group
- Resource Type
- Preprint
- Publication Details
- medRxiv
- Edition
- 1.1
- DOI
- 10.1101/2025.02.28.25323113
- PMID
- 40093231
- PMCID
- PMC11908280
- Publisher
- Cold Spring Harbor Laboratory Press
- Number of pages
- 46
- Language
- English
- Date posted
- 03/03/2025
- Academic Unit
- Emergency Medicine; Injury Prevention Research Center
- Record Identifier
- 9984802013702771
Metrics
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