Logo image
Back
Estimated prevalence of multiple chronic conditions throughout adulthood using data from the All of Us Research Program
Preprint   Open access

Estimated prevalence of multiple chronic conditions throughout adulthood using data from the All of Us Research Program

Xintong Li, Caitlin Dreisbach, Carolina M. Gustafson, Komal Patel Murali and Theresa A. Koleck
medRxiv
Cold Spring Harbor Laboratory Press, 1.1
10/18/2024
DOI: 10.1101/2024.10.17.24315661
PMCID: PMC11527047
PMID: 39484269
url
https://doi.org/10.1101/2024.10.17.24315661View
Preprint (Author's original)This preprint has not been evaluated by subject experts through peer review. Preprints may undergo extensive changes and/or become peer-reviewed journal articles. Open Access

Abstract

Estimation of multiple chronic condition (MCC) prevalence throughout adulthood provides a critical reflection of MCC burden. We analyzed electronic health record codes for 58 conditions to estimate MCC prevalence for All of Us (AoU) Research Program adult participants (N=242,828). Approximately 76% of AoU participants were diagnosed with MCCs, with over 40% having 6 or more conditions and prevalence increasing with age; the most frequently occurring MCC combinations varied by age category (i.e., mental health conditions in early adulthood and physical health conditions in middle adulthood through advanced old age). We report notable prevalence of MCC throughout adulthood and variability in MCC condition combinations by age category in AoU participants. These findings highlight the need for targeted, innovative care modalities and population health initiatives to address MCC burden throughout adulthood.
 Primary Care Research

Details

Metrics

5 Record Views
Logo image