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Spike-Adding Mechanisms in a Three-Timescale Fast-Slow System: Insights from the FitzHugh-Nagumo Model with Periodic Forcing
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Spike-Adding Mechanisms in a Three-Timescale Fast-Slow System: Insights from the FitzHugh-Nagumo Model with Periodic Forcing

Pake Melland, Rodica Curtu and Zahra Aminzare
ArXiv.org
Cornell University
10/31/2024
DOI: 10.48550/arxiv.2411.00152
url
https://doi.org/10.48550/arxiv.2411.00152View
Preprint (Author's original)This preprint has not been evaluated by subject experts through peer review. Preprints may undergo extensive changes and/or become peer-reviewed journal articles. Open Access

Abstract

In this work, we investigate the spike-adding mechanism in a class of three-dimensional fast-slow systems with three distinct timescales, inspired by the FitzHugh-Nagumo (FHN) model driven by periodic input. First, we numerically generate a bifurcation diagram for the FHN model by varying the frequency and amplitude of the input, revealing that as the frequency decreases and the amplitude increases, the number of spikes within each burst grows. Next, we apply methods from geometric singular perturbation theory to compute critical and super-critical manifolds of the fast-slow system. We use them to characterize the emergence of new burst-spikes in the FHN model, when the periodic forcing resembles a low frequency-band brain rhythm. We then describe how the uncovered spike-adding mechanism defines the boundaries that separate regions with different spike counts in the parameter space.
Mathematics - Dynamical Systems Quantitative Biology - Neurons and Cognition

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