Report
Effects of weightlessness on vestibular development in rat pups progress report, FY 1998
Scientific and technical aerospace reports, Vol.37
Tsk-10094
11/08/1999
Abstract
The lack of gravity is known to alter vestibular responses in developing and adult vertebrates. One cause of these altered responses may be changes in the connections between the vestibular receptor and the brain. Therefore, we propose to investigate the effects of gravity on the formations of connections between the gravity receptors of the ear and the brain in rat pups raised in space beginning at an age before these connections are made until near the time of birth, when they are to some extent functional. This investigation will make use of a novel technique, the diffusion of a lipophilic dye, Dil, in fixed tissue. This technique can be used to analyze the connections in specimens fixed immediately after landing of the space shuttle, thus minimizing changes due to the Earth's gravity. The evaluation of the data will enable us to detect gross deviations from normal patterns as well as detailed quantitative deviations.
Details
- Title: Subtitle
- Effects of weightlessness on vestibular development in rat pups progress report, FY 1998
- Creators
- Bernd Fritzsch - Creighton UniversityLaura L Bruce - Creighton University
- Resource Type
- Report
- Publication Details
- Scientific and technical aerospace reports, Vol.37
- Series
- Tsk-10094
- ISSN
- 1548-8837
- eISSN
- 1548-8837
- Grant note
- NCC2-861
- Language
- English
- Date published
- 11/08/1999
- Academic Unit
- Iowa Neuroscience Institute; Biology; Craniofacial Anomalies Research Center
- Record Identifier
- 9984071768902771
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