Report
Neural Control Mechanisms and Body Fluid Homeostasis
19980210970
NASA Technical Reports Server
01/01/1998
Abstract
The goal of the proposed research was to study the nature of afferent signals to the brain that reflect the status of body fluid balance and to investigate the central neural mechanisms that process this information for the activation of response systems which restore body fluid homeostasis. That is, in the face of loss of fluids from intracellular or extracellular fluid compartments, animals seek and ingest water and ionic solutions (particularly Na(+) solutions) to restore the intracellular and extracellular spaces. Over recent years, our laboratory has generated a substantial body of information indicating that: (1) a fall in systemic arterial pressure facilitates the ingestion of rehydrating solutions and (2) that the actions of brain amine systems (e.g., norepinephrine; serotonin) are critical for precise correction of fluid losses. Because both acute and chronic dehydration are associated with physiological stresses, such as exercise and sustained exposure to microgravity, the present research will aid in achieving a better understanding of how vital information is handled by the nervous system for maintenance of the body's fluid matrix which is critical for health and well-being.
Details
- Title: Subtitle
- Neural Control Mechanisms and Body Fluid Homeostasis
- Creators
- Alan Kim Johnson
- Resource Type
- Report
- Publication Details
- 19980210970
- Publisher
- NASA Technical Reports Server
- Number of pages
- 5 pages
- Language
- English
- Date published
- 01/01/1998
- Academic Unit
- Neuroscience and Pharmacology; Health and Human Physiology; Psychological and Brain Sciences
- Record Identifier
- 9984214754802771
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