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MSM White Paper: Cell Scale to Macroscale Integration
Working paper   Open access

MSM White Paper: Cell Scale to Macroscale Integration

Ching-Long Lin, George Karniadakis, James G Brasseur, Bridget S Wilson and Yi Jiang
Interagency Modeling and Analysis Group
07/2020
url
https://www.imagwiki.nibib.nih.gov/content/working-group-white-papersView
Open Access

Abstract

This white paper aims to present numerical methods that facilitate integration of subcellular and cellular scale to macroscale in the human body, and identify associated multiscale modeling issues from the numerical standpoint. Due to the complexity of the human body, the strategies for model integration may be quite different depending on specific problems. Therefore, several examples of multiscale model integration are provided in the appendices A-D.

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