Book chapter
Computational Analyses of Airway Flow and Lung Tissue Dynamics
Image-Based Computational Modeling of the Human Circulatory and Pulmonary Systems, pp.375-402
Springer US
11/03/2010
DOI: 10.1007/978-1-4419-7350-4_10
Abstract
The function of the mammalian respiratory system is the facilitation the transfer of gas exchange between the organism’s environment and its internal transport medium, the blood. Evolutionary processes have optimized the anatomic structure of the lung as a tree-like branching network of airways terminating in thin-walled elastic ducts and alveoli, where this gas exchange occurs. Both dissipative and elastic properties of the respiratory system contribute to its unique static and dynamic mechanical behavior. In this chapter, we will explore the various structural and functional relationships of the respiratory system, and review several computational and modeling analyses that provide insight into the pathophysiology of common respiratory diseases. Particular emphasis is placed on studies that utilize imaging to help understand and/or validate the distributed regional nature of lung function.
Details
- Title: Subtitle
- Computational Analyses of Airway Flow and Lung Tissue Dynamics
- Creators
- David W Kaczka - Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, USAAshley A Colletti - University of Toledo School of Medicine, Toledo, USAMerryn H Tawhai - Auckland Bioengineering Institute, The University of Auckland, Auckland, New ZealandBrett A Simon - Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, USA
- Resource Type
- Book chapter
- Publication Details
- Image-Based Computational Modeling of the Human Circulatory and Pulmonary Systems, pp.375-402
- DOI
- 10.1007/978-1-4419-7350-4_10
- Publisher
- Springer US; Boston, MA
- Language
- English
- Date published
- 11/03/2010
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Anesthesia
- Record Identifier
- 9984007297402771
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