Conditional long-term survival following minimally invasive robotic mitral valve repair: a health services perspective

Jimmy T Efird; William F Griffin; Preeti Gudimella; Wesley T O'Neal; Stephen W Davies; Patricia B Crane; Ethan J Anderson; Linda C Kindell; Hope Landrine; Jason B O'Neal; Hazaim Alwair; Alan P Kypson; Wiley L Nifong; W Randolph Chitwood Jr

doi:10.3978/j.issn.2225-319X.2015.08.08

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Conditional long-term survival following minimally invasive robotic mitral valve repair: a health services perspective

Journal article

Open access

Conditional long-term survival following minimally invasive robotic mitral valve repair: a health services perspective

Jimmy T Efird, William F Griffin, Preeti Gudimella, Wesley T O'Neal, Stephen W Davies, Patricia B Crane, Ethan J Anderson, Linda C Kindell, Hope Landrine, Jason B O'Neal, …

Annals of cardiothoracic surgery, Vol.4(5), pp.433-442

09/2015

DOI: 10.3978/j.issn.2225-319X.2015.08.08

PMCID: PMC4598467

PMID: 26539348

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Abstract

Conditional survival is defined as the probability of surviving an additional number of years beyond that already survived. The aim of this study was to compute conditional survival in patients who received a robotically assisted, minimally invasive mitral valve repair procedure (RMVP). Patients who received RMVP with annuloplasty band from May 2000 through April 2011 were included. A 5- and 10-year conditional survival model was computed using a multivariable product-limit method. Non-smoking men (≤65 years) who presented in sinus rhythm had a 96% probability of surviving at least 10 years if they survived their first year following surgery. In contrast, recent female smokers (>65 years) with preoperative atrial fibrillation only had an 11% probability of surviving beyond 10 years if alive after one year post-surgery. In the context of an increasingly managed healthcare environment, conditional survival provides useful information for patients needing to make important treatment decisions, physicians seeking to select patients most likely to benefit long-term following RMVP, and hospital administrators needing to comparatively assess the life-course economic value of high-tech surgical procedures.

minimally invasive

Conditional survival

risk-stratification

robotic

mitral valve repair

Details

Title: Subtitle: Conditional long-term survival following minimally invasive robotic mitral valve repair: a health services perspective
Creators: Jimmy T Efird - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
William F Griffin - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Preeti Gudimella - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Wesley T O'Neal - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Stephen W Davies - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Patricia B Crane - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Ethan J Anderson - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Linda C Kindell - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Hope Landrine - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Jason B O'Neal - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Hazaim Alwair - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Alan P Kypson - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Wiley L Nifong - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
W Randolph Chitwood Jr - 1 East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 2 Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 3 Department of Internal Medicine, Medical University of South Carolina, Charleston, SC, USA ; 4 Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA ; 5 Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; 6 Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ; 7 The College of Nursing at East Carolina University, Greenville, NC, USA ; 8 Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Resource Type: Journal article
Publication Details: Annals of cardiothoracic surgery, Vol.4(5), pp.433-442
Publisher: China
DOI: 10.3978/j.issn.2225-319X.2015.08.08
PMID: 26539348
PMCID: PMC4598467
ISSN: 2225-319X
eISSN: 2304-1021
Grant note: T32 GM108554 / NIGMS NIH HHS R01 HL122863 / NHLBI NIH HHS
Language: English
Date published: 09/2015
Academic Unit: Pharmaceutical Sciences and Experimental Therapeutics; Fraternal Order of Eagles Diabetes Research Center; Health and Human Physiology
Record Identifier: 9984065314002771

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