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Lung functional imaging
Journal article   Open access   Peer reviewed

Lung functional imaging

Sam Bayat, Jim Wild and Tilo Winkler
Breathe (Lausanne, Switzerland), Vol.19(3), 220272
09/01/2023
DOI: 10.1183/20734735.0272-2022
PMCID: PMC10644108
PMID: 38020338
url
https://doi.org/10.1183/20734735.0272-2022View
Published (Version of record) Open Access

Abstract

Pulmonary functional imaging modalities such as computed tomography, magnetic resonance imaging and nuclear imaging can quantitatively assess regional lung functional parameters and their distributions. These include ventilation, perfusion, gas exchange at the microvascular level and biomechanical properties, among other variables. This review describes the rationale, strengths and limitations of the various imaging modalities employed for lung functional imaging. It also aims to explain some of the most commonly measured parameters of regional lung function. A brief review of evidence on the role and utility of lung functional imaging in early diagnosis, accurate lung functional characterisation, disease phenotyping and advancing the understanding of disease mechanisms in major respiratory disorders is provided.

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