Journal article
Managing Recurrent Metastatic Head and Neck Cancer
Hematology/oncology clinics of North America, Vol.35(5), pp.1009-1020
10/01/2021
DOI: 10.1016/j.hoc.2021.05.009
PMID: 34226077
Abstract
Head and neck squamous cell carcinoma (HNSCC) treatment is often associated with high morbidity especially in the recurrent and/or metastatic (R/M) setting, limiting effective treatment options. Local disease control is important. Therefore, local therapies including reirradiation and salvage surgery, either alone or in combination with systemic treatment, may be used for selected patients with R/M HNSCC. Although chemotherapy and targeted agents have modest efficacy in HNSCC, the advent of immunotherapy has revolutionized the treatment paradigm of R/M HNSCC. Multiple trials have resulted in the past 5 years advocating for its use alone or in combination with chemotherapy.
Details
- Title: Subtitle
- Managing Recurrent Metastatic Head and Neck Cancer
- Creators
- Hira Shaikh - University of CincinnatiVidhya Karivedu - The Ohio State UniversityTrisha M. Wise-Draper - University of Cincinnati
- Resource Type
- Journal article
- Publication Details
- Hematology/oncology clinics of North America, Vol.35(5), pp.1009-1020
- Publisher
- Elsevier
- DOI
- 10.1016/j.hoc.2021.05.009
- PMID
- 34226077
- ISSN
- 0889-8588
- eISSN
- 1558-1977
- Number of pages
- 12
- Grant note
- 2UL1TR001425-05A1 / National Center for Advancing Translational Sciences of the National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Advancing Translational Sciences (NCATS) Brandon C. Gromada Head and Neck Cancer Foundation pilot grant RSG-19-111-01-CCE / American Cancer Society University of Cincinnati OH 45267-0562 / Division of Hematology/Oncology, University of Cincinnati,Eden Avenue, Cincinnati, USA OH 43210 / Division of Medical Oncology, The Ohio State University, Lincoln Tower,Cannon Drive, Columbus, USA
- Language
- English
- Date published
- 10/01/2021
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984695681002771
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