Study Design and Protocol of the Multisite Pregnancy 24/7 Cohort Study

Kara M Whitaker; Melissa A Jones; Karina Smith; Janet Catov; Maisa Feghali; Christopher E Kline; Mark Santillan; Donna Santillan; Bridget Zimmerman; Bethany Barone Gibbs

doi:10.1093/aje/kwad208

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Study Design and Protocol of the Multisite Pregnancy 24/7 Cohort Study

Journal article

Peer reviewed

Study Design and Protocol of the Multisite Pregnancy 24/7 Cohort Study

Kara M Whitaker, Melissa A Jones, Karina Smith, Janet Catov, Maisa Feghali, Christopher E Kline, Mark Santillan, Donna Santillan, Bridget Zimmerman and Bethany Barone Gibbs

American journal of epidemiology, Vol.193(3), pp.415-425

03/04/2024

DOI: 10.1093/aje/kwad208

PMCID: PMC11484610

PMID: 37939072

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https://pmc.ncbi.nlm.nih.gov/articles/PMC11484610/pdf/kwad208.pdfView

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Abstract

Abstract Hypertensive disorders of pregnancy and other adverse pregnancy outcomes (APOs) are associated with an increased risk of future maternal cardiovascular disease. Physical activity during pregnancy reduces the risk of these APOs, yet few meet physical activity guidelines during pregnancy. Little is known about the role of sedentary behavior (SB) or sleep in APOs, a critical gap in knowledge given these behaviors comprise the majority of a 24-hour day. To address this knowledge gap, the Pregnancy 24/7 cohort study (2020-2025) uses two devices for 24-hour activity assessment in each trimester of pregnancy to examine associations of SB, sleep, and the 24-hour activity cycle (composition of SB, physical activity, and sleep) with hypertensive disorders and other APOs. Participants (N=500) are recruited from the University of Iowa, University of Pittsburgh, and West Virginia University in early pregnancy and followed through delivery. The activPAL3 micro and Actiwatch Spectrum Plus are worn in each trimester for 7 days of 24-hour wear to assess the 24-hour activity cycle. APOs are abstracted from medical charts. This study will provide critical data to fuel future research examining how modifying the 24-hour activity cycle in pregnancy can improve maternal health.

Details

Title: Subtitle: Study Design and Protocol of the Multisite Pregnancy 24/7 Cohort Study
Creators: Kara M Whitaker - University of Iowa
Melissa A Jones - Oakland University
Karina Smith - University of Iowa
Janet Catov - University of Pittsburgh
Maisa Feghali - University of Pittsburgh
Christopher E Kline - University of Pittsburgh
Mark Santillan - University of Iowa
Donna Santillan - University of Iowa
Bridget Zimmerman - University of Iowa
Bethany Barone Gibbs - West Virginia University
Resource Type: Journal article
Publication Details: American journal of epidemiology, Vol.193(3), pp.415-425
DOI: 10.1093/aje/kwad208
PMID: 37939072
PMCID: PMC11484610
NLM abbreviation: Am J Epidemiol
ISSN: 0002-9262
eISSN: 1476-6256
Language: English
Electronic publication date: 11/03/2023
Date published: 03/04/2024
Academic Unit: Epidemiology; Biostatistics; Obstetrics and Gynecology; Health, Sport, and Human Physiology
Record Identifier: 9984507026002771

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